Stem Cells & Biomaterials
At the heart of our stem cell efforts is the Sudhakar & Sreekanth Ravi Stem Cell Biology Laboratory, set up with the generous support of two brothers – Sudhakar Ravi and Sreekanth Ravi of California, USA. The lab is engaged in frontline research designed to apply knowledge of stem cell biology to the treatment of eye diseases.
Principle investigators
Dr Sayan Basu is the Prof. D Balasubramanian Chair of Eye Research, the Director of Prof. Brien Holden Eye Research Centre (BHERC), and the Director of Centre for Ocular Regeneration (CORE).
He is a clinician-scientist and a key opinion leader in the field of Cornea and Ocular Surface and is internationally recognized for his innovative breakthroughs in corneal stem cell therapy.
Dr Vivek Singh’s lab combines various cell biology, molecular biology, and bioengineering approaches to address the scientific questions mainly related to ocular surface diseases.
Vivek’s research focuses on corneal wound healing, Dry eye disease, Stevens-Johnson syndrome, and simple limbal epithelial transplantation.
Dr. Vineet Joshi serves as the Clinical Lead at LVPEI’s Centre for Technology and Innovation. He works with engineers and designers to develop advanced medical devices and technologies.
Vineet is passionate about corneal surgeries and bioengineering, particularly in lamellar corneal surgeries and corneal transplants. He is actively involved in corneal bioengineering and 3D bioprinting of artificial corneas.
Dr Charanya Ramachandran pursues research work on the ‘corneal endothelium’. This includes understanding the mechanisms driving endothelial dysfunction, generating cells for transplantation into patients and developing materials to aid transplantation.
She was part of the design and execution of a clinical trial to test the safety and efficacy of the biomaterials in humans.
Dr. Sachin Shukla received the DST-INSPIRE Faculty award by the Department of Science and Technology, Government of India and worked on corneal repair, regeneration, and immunomodulation using adult mesenchymal stem cells (MSC) and limbal stem cells.
His research interests focus on mesenchymal stem cell-based corneal repair and ocular immunology.
Publications
3D Bioprinting & Biomaterials Lab
A state-of-the-art lab for novel biomaterials and cellular models, personalised 3D-bioprinted corneal tissues and more…
Deeksha Prasad
Jilu Jaffet
Tejaswini Pingali
Aniruth Reddy
Suraj K Rajak
Sonali Mahapatra
Rohini Sonar
Sahithi Macherla
Parul Chaurasia
Mahalakshmi Yadavalli
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