The Centre for Ocular Regeneration

biomaterials

The Centre for Ocular Regeneration is an LVPEI ‘Institute of Excellence’ with the ambition to be a global resource centre for cell and gene-based approaches to sight restoration.

The Research teams at LVPEI have made deep investments in exploring cell and gene therapies that tackle various kinds of vision loss. Approaches that benefit from the latest advances in stem cell therapies, including induced pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs), to support ocular surface reconstruction and regenerating the retinal epithelium.

Research Pipeline

  • Corneal wound healing
  • Animal model for ocular surface pathology
  • Stem cell and regenerative medicine
  • Ocular surface inflammatory disorders 
  • Dry eye disease 
  • Therapeutic Potential of Mesenchymal Stem Cells, their secretomes and extracellular vesicles
  • Biomimetic cornea
  • Corneal endothelium: Physiology, Pathobiology and Tissue Engineering
  • Ocular allergies
  • Bacterial keratitis
  • iPSCs, retina
100+
Papers published

6
patents applied
3
Clinical Trials

Key research areas

Our teams explore stem cell therapies for corneal wound healing, Dry eye disease, Steven-Johnson syndrome, and various inherited retinal diseases.

Apart from stem cell therapies, we also work on biomaterials research (including 3D bioprinting) and gene-editing technologies.